Experienta profesionala:

• 2012 – 2014: medic rezident specialitatea Cardiologie – Spitalul de urgenta Floreasca
• 2014 – 2015: bursiera a Societatii Europene de Cardiologie  – program de training in electrofiziogie    cardiaca interventionala Klinikum Ludwigsburg, Baden – Württenberg, Germania
• 2015 – 2017: medic rezident cardiologie/electrofiziologie – Rhön-Klinikum AG, Campus Bad Neustadt
• 2018 – present: medic primar cardiolog, electrofiziologie cardiaca interventionala, Clinica de Cardiologie II – Electrofiziologie cardiaca interventionala, Rhön-Klinikum AG, Campus Bad Neustadt

• Coordonator program fellowship international in electrofiziologie cardiaca interventionala in cadrul sectiei de Cardiologie II cu electrofiziologie interventionala – Rhön-Klinikum AG, Campus Bad Neustadt
• Coordonator unitate tahicardii ventriculare (VT unit)

 

Portofoliu proceduri si investigatii:

• Consultatii aritmologie, ecografie transtoracica, test de efort, holter EKG, holter TA
• Controale si programare dispositive cardiace implantabile (stimulator, defibrillator)
• Cardioversii electrice
• Implant loop recorder
• Ablatii tahicardii supraventriculare (reintrare intranodala, tahicardii focale, caii accesorii – sdr WPW)
• Ablatii fibrilatie atriala (radiofrecventa, electroporatie) si aritmii atriale complexe de atriu stang si drept (post chirurgie cardiaca)
• Ablatii tahicardii ventriculare inclusiv cu abord epicardic si integrare imagistica intraprocedurala
• Ablatii aritmii la pacientii pediatrici
• 4800 Proceduri de electrofiziologie cardiaca interventionala effectuate

Domenii de expertiza: ablatii de aritmii  complexe ventriculare si supraventriculare

Activitate stiintifica:

• Co – investigator in 19 studii clinice multicentrice, internationale printer care BERLIN VT, PARTITA, PROTECT-ICD, HEAT AF, RESET -CRT
• Investigator principal in 3 studii multicentrice, randomizate – BEAT AF PAROX, BEAT AF PERSIST si InEurHeart
• Atestat investigator pentru studii clinice cu medicamente
• Atestat investigator pentru studii clinice cu dispozitive medicale

 

Articole publicate:

• Nentwich K, Klingel K, Ene E, Müller J, Berkowitz A, Barth S, Deneke T. Cardiac sarcoidosis in patients with recurrent ventricular arrhythmias refractory to endocardial ablation. Clin Res Cardiol. 2024 Aug 27. doi: 10.1007/s00392-024-02509-z. Online ahead of print.PMID: 39190185

• Lenarczyk R, Zeppenfeld K, Tfelt-Hansen J, Heinzel FR, Deneke T, Ene E, Meyer C, Wilde A, Arbelo E, Jędrzejczyk-Patej E, Sabbag A, Stühlinger M, di Biase L, Vaseghi M, Ziv O, Bautista-Vargas WF, Kumar S, Namboodiri N, Henz BD, Montero-Cabezas J, Dagres N, Peichl P, Frontera A, Tzeis S, Merino JL, Soejima K, de Chillou C, Tung R, Eckardt L, Maury P, Hlivak P, Tereshchenko LG, Kojodjojo P, Atié J. Management of patients with an electrical storm or clustered ventricular arrhythmias: a clinical consensus statement of the European Heart Rhythm Association of the ESC-endorsed by the Asia-Pacific Heart Rhythm Society, Heart Rhythm Society, and Latin-American Heart Rhythm Society. 2024 Mar 30;26(4):euae049. doi: 10.1093/europace/euae049.PMID: 38584423 

• Mueller J, Chakarov I, Halbfass P, Nentwich K, Ene E, Berkovitz A, Sonne K, Barth S, Waechter C, Behnes M, Akin I, Fodor S, Lehmkuhl L, Deneke T. Adverse Prognosis of Patients With Septal Substrate After VT Ablation Due to Electrical Storm.JACC Clin Electrophysiol. 2023 Jun;9(6):790-804. doi: 10.1016/j.jacep.2023.01.012. Epub 2023 Mar 22.PMID: 36951814 

• Müller J, Nentwich K, Berkovitz A, Ene E, Sonne K, Zhuravlev V, Chakarov I, Barth S, Waechter C, Behnes M, Halbfass P, Deneke T. Acute oesophageal safety and long-term follow-up of AI-guided high-power short-duration with 50 W for atrial fibrillation ablation. 2023 Apr 15;25(4):1379-1391. doi: 10.1093/europace/euad053.PMID: 36881791 

• Mueller J, Chakarov I, Halbfass P, Nentwich K, Ene E, Berkovitz A, Sonne K, Barth S, Waechter C, Schupp T, Behnes M, Akin I, Deneke T. Electrical Storm Has Worse Prognosis Compared to Sustained Ventricular Tachycardia after VT Ablation.J Clin Med. 2023 Apr 6;12(7):2730. doi: 10.3390/jcm12072730.PMID: 37048813 

• Mueller J, Nentwich K, Ene E, Berkovitz A, Sonne K, Chakarov I, Barth S, Waechter C, Behnes M, Akin I, Halbfass P, Deneke T. Radiofrequency ablation of atrial fibrillation-50 W or 90 W? J Cardiovasc Electrophysiol. 2022 Dec;33(12):2504-2513. doi: 10.1111/jce.15681. Epub 2022 Oct 8.PMID: 36124396

• Simu G, Deneke T, Ene E, Nentwich K, Berkovitz A, Sonne K, Halbfass P, Arvaniti E, Waechter C, Müller J. Empirical superior vena cava isolation in patients undergoing repeat catheter ablation procedure after recurrence of atrial fibrillation. J Interv Card Electrophysiol. 2022 Nov;65(2):551-558. doi: 10.1007/s10840-022-01301-1. Epub 2022 Jul 20.PMID: 35857220

• Ene E, Halbfaß P, Nentwich K, Sonne K, Berkovitz A, Cochet H, Jais P, Lehmkuhl L, Foldyna B, Deneke T. Optimal cut-off value for endocardial bipolar voltage mapping using a multipoint mapping catheter to characterize the scar regions described in cardio-CT with myocardial thinning. J Cardiovasc Electrophysiol. 2022 Oct;33(10):2174-2180. doi: 10.1111/jce.15651. Epub 2022 Aug 23.PMID: 35938384

 

• Müller J, Berkovitz A, Halbfass P, Nentwich K, Ene E, Sonne K, Simu G, Chakarov I, Barth S, Waechter C, Behnes M, Akin I, Deneke T. Acute oesophageal safety of high-power short duration with 50 W for atrial fibrillation ablation. 2022 Jul 15;24(6):928-937. doi: 10.1093/europace/euab329.PMID: 35134155

• Kany S, Alken FA, Schleberger R, Baran J, Luik A, Haas A, Ene E, Deneke T, Dinshaw L, Rillig A, Metzner A, Reissmann B, Makimoto H, Reents T, Popa MA, Deisenhofer I, Piotrowski R, Kulakowski P, Kirchhof P, Scherschel K, Meyer C. Bipolar ablation of therapy-refractory ventricular arrhythmias: application of a dedicated approach. 2022 Jul 15;24(6):959-969. doi: 10.1093/europace/euab304.PMID:34922350 

• Chakarov I, Mueller J, Ene E, Berkovitz A, Sonne K, Nentwich K, Schupp T, Behnes M, Deneke T. Long-Term Outcomes after Catheter Ablation of Ventricular Tachycardia in Dilated vs. Ischemic Cardiomyopathy. J Clin Med. 2022 Jul 11;11(14):4000. doi: 10.3390/jcm11144000.PMID:35887764 

• Nentwich K, Ene E, Müller J, Berkowitz A, Kerber S, Deneke T. Case report: Epicardial ligation of the left atrial appendage in a patient with an inaccessible left atrial cavity.J Cardiovasc Electrophysiol. 2022 Jul;33(7):1596-1598. doi: 10.1111/jce.15561. Epub 2022 Jun 4.PMID:35612359

• Müller J, Nentwich K, Berkovitz A, Ene E, Sonne K, Chakarov I, Barth S, Waechter C, Lüsebrink U, Behnes M, Akin I, Deneke T. Efficacy and safety of high-power short duration atrial fibrillation ablation in elderly patients.J Cardiovasc Electrophysiol. 2022 Jul;33(7):1425-1434. doi: 10.1111/jce.15504. Epub 2022 May 6.PMID:35441414

• Ene E, Didenko M, Berkovitz A, Nentwich K, Sonne K, Zhuravlev V, Deneke T. Relevant anatomy of epicardial space for the electrophysiologists].Herzschrittmacherther Elektrophysiol. 2022 Jun;33(2):175-180. doi: 10.1007/s00399-022-00856-w. Epub 2022 May 13.PMID:35556155  German.

• Mueller J, Halbfass P, Sonne K, Nentwich K, Ene E, Berkovitz A, Lehmkuhl L, Barth S, Simu GR, Waechter C, Behnes M, Deneke T. Safety aspects of very high power very short duration atrial fibrillation ablation using a modified radiofrequency RF-generator: Single-center experience. J Cardiovasc Electrophysiol. 2022 May;33(5):920-927. doi: 10.1111/jce.15433. Epub 2022 Mar 11.PMID:35233883

• Halbfass P, Wielandts JY, Knecht S, Le Polain de Waroux JB, Tavernier R, De Wilde V, Sonne K, Nentwich K, Ene E, Berkovitz A, Mueller J, Lehmkuhl L, Reichart A, Lüsebrink U, Duytschaever M, Deneke T. Safety of very high-power short-duration radiofrequency ablation for pulmonary vein isolation: a two-centre report with emphasis on silent oesophageal injury. 2022 Mar 2;24(3):400-405. doi: 10.1093/europace/euab261.PMID:34757432

• Halbfass P, Ludwig D, Sonne K, Nentwich K, Ene E, Berkovitz A, Foldyna B, Barth S, Müller J, Lehmkuhl L, Lüsebrink U, Waechter C, Deneke T. Acute and long-term outcomes of VT radiofrequency catheter ablation in patients with versus without an intramural septal substrate. Indian Pacing Electrophysiol J. 2022 Jan-Feb;22(1):2-9. doi: 10.1016/j.ipej.2021.10.002. Epub 2021 Oct 14.PMID:34655759 

• Deneke T, Berkovitz A, Ene E, Sonne K, Simu G, Müller J, Lehmkuhl L, Müller M, Nentwich K. A 19-year-old woman with palpitations and mitral regurgitation. Herzschrittmacherther Elektrophysiol. 2021 Dec;32(4):471-474. doi: 10.1007/s00399-021-00823-x. Epub 2021 Oct 29.PMID:34714388 

• Deneke T, Sonne K, Ene E, Berkovitz A, Nentwich K. Esophagopericardial Fistula: The Wolf in Sheep’s Clothing.JACC Case Rep. 2021 Jul 21;3(8):1136-1138. doi: 10.1016/j.jaccas.2021.04.043. eCollection 2021 Jul 21.PMID:34471898 

 

• Nentwich K, Ene E, Halbfass P, Berkowitz A, Sonne K, Kerber S, Lee R, Deneke T. Concomitant epicardial left atrial appendage ligation and left atrial ablation of atrial fibrillation: Safety, feasibility and outcome. Indian Pacing Electrophysiol J. 2021 Mar-Apr;21(2):75-79. doi: 10.1016/j.ipej.2021.01.001. Epub 2021 Jan 15.PMID:33460777 

• Piringer R, Deneke T, Foldyna B, Sonne K, Nentwich K, Ene E, Barth S, Lüsebrink U, Berkovitz A, Halbfass P.J Cardiovasc Electrophysiol. Incidence of ablation-induced esophageal injury associated with high-power short duration temperature-controlled pulmonary vein isolation using a specialized open-irrigated ablation catheter: A retrospective single-center study.2021 Mar;32(3):695-703. doi: 10.1111/jce.14883. Epub 2021 Jan 23.PMID: 33442930

• Halbfass P, Lehmkuhl L, Foldyna B, Berkovitz A, Sonne K, Nentwich K, Ene E, Fochler F, Hörning F, Matveeva A, Lüsebrink U, Deneke T. Correlation of magnetic resonance imaging and post-ablation endoscopy to detect oesophageal thermal injury in patients after atrial fibrillation ablation: MRI-EDEL-study. 2020 Jul 1;22(7):1009-1016. doi: 10.1093/europace/euaa081.PMID:32428229

• Deneke T, Nentwich K, Ene E, Berkovitz A, Sonne K, Halbfaß P.Acute management of ventricular tachycardia. Herzschrittmacherther Elektrophysiol. 2020 Mar;31(1):26-32. doi: 10.1007/s00399-020-00664-0. Epub 2020 Feb 6.PMID:32030516  English.

• Halbfass P, Berkovitz A, Pavlov B, Sonne K, Nentwich K, Ene E, Hoerning F, Barth S, Zacher M, Deneke T. Incidence of acute thermal esophageal injury after atrial fibrillation ablation guided by prespecified ablation index. J Cardiovasc Electrophysiol. 2019 Nov;30(11):2256-2261. doi: 10.1111/jce.14193. Epub 2019 Sep 30.PMID:31559655

• Berkovitz A, Deneke T, Ene E, Halbfaß P, Hebe J, Hobbiesiefken S, Katus HA, Konrad T, Lange B, Marx A, Nentwich K, Neuzner J, Paliege R, Reinhardt A, Rostock T, Siebels J, Scholz EP, Sonne K. Ventricular extrasystoles and wide complex tachycardias. Herzschrittmacherther Elektrophysiol. 2019 Mar;30(1):38-50. doi: 10.1007/s00399-019-0612-4. Epub 2019 Mar 8.PMID:30848338  German. No abstract available.

• Deneke T, Nentwich K, Berkovitz A, Sonne K, Ene E, Pavlov B, Fochler F, Bötsch AK, Kuhn R, Halbfaß P High-Resolution Infrared Thermal Imaging of the Esophagus During Atrial Fibrillation Ablation as a Predictor of Endoscopically Detected Thermal Lesions: Results From the HEAT-AF Study. Circ Arrhythm Electrophysiol. 2018 Nov;11(11):e006681. doi: 10.1161/CIRCEP.118.006681.PMID: 30376732

• Deneke T, Mügge A, Ene E, Nentwich K, Halbfaß P. Catheter Ablation of Ventricular Tachycardia in Nonischemic Cardiomyopathy: The Relevance of Pathology Subtype and Experience of Centers: The More the Better? JACC Clin Electrophysiol. 2018 Sep;4(9):1151-1154. doi: 10.1016/j.jacep.2018.06.013.PMID:30236387 

• Ene E, Halbfaß P, Nentwich K, Sonne K, Berkovitz A, Wolf AK, Deneke T. Epicardial VT ablation : In whom, when, how and why? . Herzschrittmacherther Elektrophysiol. 2018 Sep;29(3):300-306. doi: 10.1007/s00399-018-0578-7. Epub 2018 Jun 26.PMID:29946891  German.

• Halbfass P, Sonne K, Nentwich K, Ene E, Deneke T Current developments in cardiac rhythm management devices. Clin Res Cardiol. 2018 Aug;107(Suppl 2):100-104. doi: 10.1007/s00392-018-1313-4. Epub 2018 Jun 27.PMID:29951805 

• Halbfass P, Nentwich K, Krug J, Roos M, Sonne K, Ene E, Hamm K, Barth S, Szöllösi A, Fochler F, Mügge A, Lüsebrink U, Deneke T. Impact of surround flow catheter tip irrigation in contact force ablation on the incidence of asymptomatic oesophageal lesions after atrial fibrillation ablation: a prospective comparative study. 2017 Jul 1;19(7):1116-1122. doi: 10.1093/europace/euw119.PMID:27353324

• Ene E, Halbfaß P, Nentwich K, Sonne K, Roos M, Fodor S, Lehmkuhl L, Gietzen F, Barth S, Hamm K, Deneke T. [Epicardial ablation of ventricular tachycardias].Herzschrittmacherther Elektrophysiol. 2017 Jun;28(2):212-218. doi: 10.1007/s00399-017-0501-7. Epub 2017 May 9.PMID:28488109  German.

• Halbfaß P, Nentwich K, Sonne K, Ene E, Fochler F, Mügge A, Schieffer B, Deneke T. Catheter ablation of ventricular extrasystoles and ventricular tachycardia in the elderly]. Herzschrittmacherther Elektrophysiol. 2017 Mar;28(1):9-15. doi: 10.1007/s00399-017-0483-5. Epub 2017 Feb 7.PMID:28175981  German.

 

 Capitole carti:

1). Capitolul 3. METODE MODERNE DE EVALUARE A BOLNAVULUI CU INSUFICIENŢĂ

CARDIACĂ CRONICĂ – 3.2. Evaluarea dissincronismului cardiac, Elena Ene, Radu Vătăşescu in INSUFICIENŢA CARDIACĂ.VECHEA ŞI NOUA PARADIGMĂ

EDITURA ACADEMIEI ROMÂNE, Bucureşti, 2015, ISBN 978-973-27-2532-0

2). “Approach to ventricular arrhythmia in heart failure”. Elena Ene, Thomas Deneke

second edition of Current Approach to Heart Failure  Edited by Maria Dorobanțu, Piotr Ponikowski and Frank Rushitzka.

3). Behandlung ventrikulärer Herz-Rhythmusstörungen UNI-MED Verlag AG

Bremen – London – Boston Ablation von Kammerarrhythmien bei Patienten mit struktureller Herzerkrankung, 2018, ISBN: 978-3-8374-5564-9

 

4). “Indrazniti sa ganditi dincolo de aparente: managementul integrativ al unui caz de furtuna electrica bazat pe imagistica cardiaca intr-un caz de disfunctie miocardica de etiologie „neelucidata“ in Cardiologia de urgenta. De la prezent la viitor. Maria Dorobantu, Sebastian Onciul. Editura medicala. 2019, ISBN: 9733908711

Activitate didactica – cursuri organizate:

Co – director de curs (2021, 2022, 2023) – Modulul  4  “Aritmii ventriculare ” organizat de Academia Societatii Germane de Cardiologie, in cadrul curiculei nationale pentru obtinerea  competentei  in electrofiziologie cardiaca a Societatii Germane de Cardiologie

Prezentari si cursuri periodice pentru medici rezidenti si student medicina

Prezentari periodice in cadrul conferintei de morbiditate si mortalitate a  Clinicii de Cardiologie, Rhön Klinikum AG, Campus Bad Neustadt